about acc

Basic information about agenesis of the corpus callosum


About ACC

What is Agenesis of the Corpus Callosum (ACC/AgCC)?
ACC is a brain malformation that occurs before birth. Children with ACC are missing some (partial ACC) or all (complete ACC) of the corpus callosum, which connects the two halves of the brain. If the corpus callosum forms but is abnormally thin, it is called ‘hypogenesis’ or ‘hypoplasia.’

How is ACC diagnosed?
ACC can only be diagnosed by a brain scan (MRI, CT, or ultrasound).
What causes ACC?
Disruptions in development of the corpus callosum occur between the 5th and 16th weeks of pregnancy. Multiple factors can disrupt this development including: prenatal infections and viruses, genetic abnormalities, toxic metabolic conditions, and blockage of the growth of the corpus callosum (for example, cysts).
What is dysgenesis of the corpus callosum (DCC)?
DCC is the umbrella term for various types of callosum malformations including complete ACC, partial ACC, and hypoplasia.
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